Most modern Ham Radio Rigs provide a CAT (Computer Assisted Tuning) interface which offer the ability to control the radio from a computer.

A good number of CAT interfaces are based on protocols layered on the standard serial interface.

Cables including a USB to serial converter are readily available on ebay for about £9 including shipping:

Both cables are based on the Prolific PL2303 chipset - drivers for both Windows and Unix available on the Prolific website Prolific